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QuickView for angelman syndrome;jsessionid=40D8B3B94AF3590FEFBE55E41A08856D (gene)


Gene Symbol:
Ube3a Rattus norvegicus Rattus norvegicus
Full name:
ubiquitin protein ligase E3A
Synonyms:
ubiquitin-protein ligase E3A
Genomic Location:
Chr 1: 110729607-110814062
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
MEF2_01 YY1_01 AAGWWRNYGGC_UNKNOWN GATA1_03 GATA1_04 OCT1_05 AP1FJ_Q2 AP1_Q2 AP1_Q4 GATA_C
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | transcription coactivator activity | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | transcription coregulator activity

GO Biological Process

positive regulation of macromolecule biosynthetic process | regulation of cell morphogenesis | regulation of neurogenesis | developmental process involved in reproduction | ovarian follicle development | proteolysis | regulation of cell development | prostate gland growth | gonad development | female gonad development | establishment of localization | response to hormone | negative regulation of cellular process | cell differentiation | negative regulation of dendrite development | nervous system development | response to drug | androgen receptor signaling pathway | organ growth | neurogenesis | generation of neurons | response to antibiotic | hormone-mediated signaling pathway | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | regulation of dendritic spine morphogenesis | localization | proteolysis involved in cellular protein catabolic process | developmental growth | negative regulation of synapse organization | reproductive system development | response to progesterone | regulation of proteolysis | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | response to inorganic substance | regulation of cell differentiation | response to hydrogen peroxide | regulation of cellular process | cellular response to lipid | regulation of metabolic process | catabolic process | response to nerve growth factor | positive regulation of cellular protein metabolic process | negative regulation of cell morphogenesis involved in differentiation | urogenital system development | development of primary sexual characteristics | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to cocaine | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | negative regulation of dendritic spine morphogenesis | negative regulation of neuron projection development | regulation of protein ubiquitination | development of primary female sexual characteristics | reproduction | cellular protein catabolic process | proteasomal protein catabolic process | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | protein modification process | steroid hormone mediated signaling pathway | regulation of synapse structure or activity | macromolecule modification | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | negative regulation of dendritic spine development | cellular response to nerve growth factor stimulus | regulation of neuron differentiation | regulation of gene expression | response to ketone | response to lipid | protein catabolic process | positive regulation of cellular metabolic process | progesterone receptor signaling pathway | response to ammonium ion | regulation of synapse organization | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of transcription by RNA polymerase II | response to oxidative stress | ubiquitin protein ligase activity | negative regulation of dendrite morphogenesis | regulation of cellular protein metabolic process | fertilization | response to toxic substance | response to xenobiotic stimulus | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | transcription coactivator activity | regulation of RNA metabolic process | single fertilization | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | regulation of cell morphogenesis involved in differentiation | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | sperm entry | negative regulation of cell projection organization | protein ubiquitination | import into cell | regulation of intracellular signal transduction | cellular macromolecule catabolic process | protein autoubiquitination | anatomical structure development | regulation of dendrite morphogenesis | metabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of RNA biosynthetic process | endocytosis | organic substance metabolic process | animal organ development | response to reactive oxygen species | negative regulation of neuron differentiation | cellular response to brain-derived neurotrophic factor stimulus | protein modification by small protein conjugation or removal | response to alkaloid | cellular response to steroid hormone stimulus | regulation of postsynapse organization | intracellular receptor signaling pathway | ubiquitin-dependent protein catabolic process | regulation of dendrite development | organonitrogen compound catabolic process | regulation of cell communication | regulation of dendritic spine development | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | prostate gland development | regulation of circadian rhythm | reproductive structure development | regulation of nervous system development | regulation of developmental process | developmental process | intracellular steroid hormone receptor signaling pathway | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | protein K48-linked ubiquitination | response to anesthetic | positive regulation of metabolic process | regulation of cell projection organization | cellular metabolic process | female sex differentiation | cellular response to organic substance | sex differentiation | response to steroid hormone | modification-dependent protein catabolic process | negative regulation of cell development | regulation of ubiquitin-dependent protein catabolic process | sexual reproduction | positive regulation of protein ubiquitination | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular